ICD-10-CM 2027 diagnosis code
N12Tubulo-interstitial nephritis, not specified as acute or chronic
N12 is a valid, billable ICD-10-CM code for tubulo-interstitial nephritis, not specified as acute or chronic. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.Short description: Tubulo-interstitial nephritis, not spcf as acute or chronic
Looking up by condition? See ICD-10 code for Pyonephritis, ICD-10 code for Nonobstructive pyelonephritis.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About N12
N12 is the ICD-10-CM diagnosis code for tubulo-interstitial nephritis, not specified as acute or chronic. It belongs to block N10-N16 (renal tubulo-interstitial diseases) and chapter 14 (diseases of the genitourinary system). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
Don't report N12 together with the conditions in its Excludes1 note: calculous pyelonephritis (N20.9).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 689 (Kidney and Urinary Tract Infections with MCC, relative weight 1.1415), DRG 690 (Kidney and Urinary Tract Infections without MCC, relative weight 0.801), DRG 791 (Prematurity with Major Problems, relative weight 4.1075) and DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195), in MDC 11 (Diseases and Disorders of the Kidney and Urinary Tract) and MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Before ICD-10, this condition was coded in ICD-9-CM as 590.80 (pyelonephritis, unspecified).
Coding notes
- Interstitial nephritis NOS
- Pyelitis NOS
- Pyelonephritis NOS
- calculous pyelonephritis (N20.9)
Notes that apply from higher levels
Instructions written at a parent level also apply to N12.
Broader instructions also apply from N10-N16 Renal tubulo-interstitial diseases and Chapter 14: Diseases of the genitourinary system.
Alphabetic index entries
6 entriesTerms in the official ICD-10-CM index that lead to N12.
- Disease, diseased › antiglomerular basement membrane (anti- GBM) antibody › tubulo-interstitial nephritis
- Disease, diseased › renal (functional) (pelvis) › with › interstitial nephritis
- Nephritis, nephritic (albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic) › antitubular basement membrane (tubulo-interstitial) NEC
- Nephritis, nephritic (albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic) › tubulo-interstitial (in)
- Pyelonephritis › nonobstructive
- Pyonephritis
Codes whose notes reference N12
- N05Excludes1
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC 11 · Diseases and Disorders of the Kidney and Urinary Tract
MDC 15 · Newborns and Other Neonates with Conditions Originating in the Perinatal Period
MDC 15 · Newborns and Other Neonates with Conditions Originating in the Perinatal Period
ICD-9-CM equivalent
Converter →- 590.80Pyelonephritis, unspecifiedapproximate
From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about N12
Is N12 billable?
- Yes. N12 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can N12 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict N12 as a principal diagnosis.
Is N12 a CC or MCC?
- N12 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.
What DRG does N12 group to?
- N12 is used in the MS-DRG v44.0 logic for MS-DRG 689 (Kidney and Urinary Tract Infections with MCC), MS-DRG 690 (Kidney and Urinary Tract Infections without MCC), MS-DRG 791 (Prematurity with Major Problems) and MS-DRG 793 (Full Term Neonate with Major Problems). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.
What is the ICD-9 code for N12?
- The CMS General Equivalence Mappings map N12 to ICD-9-CM 590.80.