N40.3Nodular prostate with lower urinary tract symptoms

N40.3 is the ICD-10-CM diagnosis code for nodular prostate with lower urinary tract symptoms. It belongs to category N40 (benign prostatic hyperplasia), block N40-N53 (diseases of male genital organs) and chapter 14 (diseases of the genitourinary system). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within N40 (benign prostatic hyperplasia), N40.3 is specifically for nodular prostate with lower urinary tract symptoms. Related codes cover without lower urinary tract symptoms (N40.0), with lower urinary tract symptoms (N40.1) and nodular prostate without lower urinary tract symptoms (N40.2).

Use an additional code for associated symptoms, when specified: incomplete bladder emptying (R39.14), nocturia (R35.1), straining on urination (R39.16), urinary frequency (R35.0), urinary hesitancy (R39.11) and 5 more.

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 725 (Benign Prostatic Hypertrophy with MCC, relative weight 1.1578) and DRG 726 (Benign Prostatic Hypertrophy without MCC, relative weight 0.7252), in MDC 12 (Diseases and Disorders of the Male Reproductive System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

The Medicare Code Editor expects this diagnosis only for patients age 15 through 124.

It is on the CMS list of diagnoses consistent only with male patients (the sex-conflict edit itself was retired in FY2025).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 600.11 (nodular prostate with urinary obstruction).