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ICD-10-CM 2027 diagnosis code

N46.01Organic azoospermia

✓ Billable / specificAdult · age 15–124Male only

N46.01 is a valid, billable ICD-10-CM code for organic azoospermia. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Looking up by condition? See ICD-10 code for Azoospermia.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About N46.01

N46.01 is the ICD-10-CM diagnosis code for organic azoospermia. It belongs to category N46 (male infertility), block N40-N53 (diseases of male genital organs) and chapter 14 (diseases of the genitourinary system). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within N46.0 (azoospermia), N46.01 is specifically for organic azoospermia. Related codes cover due to extratesticular causes (N46.02).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 729 (Other Male Reproductive System Diagnoses with CC/MCC, relative weight 1.0544) and DRG 730 (Other Male Reproductive System Diagnoses without CC/MCC, relative weight 0.6597), in MDC 12 (Diseases and Disorders of the Male Reproductive System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

The Medicare Code Editor expects this diagnosis only for patients age 15 through 124.

It is on the CMS list of diagnoses consistent only with male patients (the sex-conflict edit itself was retired in FY2025).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 606.0 (azoospermia).

Coding notes

Applicable toConditions and synonyms classified to this code
  • Azoospermia NOS

Notes that apply from higher levels

Instructions written at a parent level also apply to N46.01.

› From N46 Male infertility
Excludes1

Broader instructions also apply from Chapter 14: Diseases of the genitourinary system.

Alphabetic index entries

2 entries

Terms in the official ICD-10-CM index that lead to N46.01.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 606.0Azoospermiaapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about N46.01

Is N46.01 billable?

Yes. N46.01 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can N46.01 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict N46.01 as a principal diagnosis.

Is N46.01 a CC or MCC?

No. N46.01 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does N46.01 group to?

N46.01 is used in the MS-DRG v44.0 logic for MS-DRG 729 (Other Male Reproductive System Diagnoses with CC/MCC) and MS-DRG 730 (Other Male Reproductive System Diagnoses without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for N46.01?

The CMS General Equivalence Mappings map N46.01 to ICD-9-CM 606.0.