N52.35Erectile dysfunction following radiation therapy

N52.35 is the ICD-10-CM diagnosis code for erectile dysfunction following radiation therapy. It belongs to category N52 (male erectile dysfunction), block N40-N53 (diseases of male genital organs) and chapter 14 (diseases of the genitourinary system). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within N52.3 (postprocedural erectile dysfunction), N52.35 is specifically for erectile dysfunction following radiation therapy. Related codes cover erectile dysfunction following radical prostatectomy (N52.31), erectile dysfunction following radical cystectomy (N52.32), erectile dysfunction following urethral surgery (N52.33), erectile dysfunction following simple prostatectomy (N52.34), erectile dysfunction following interstitial seed therapy (N52.36), erectile dysfunction following prostate ablative therapy (N52.37) and other and unspecified postprocedural erectile dysfunction (N52.39).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 729 (Other Male Reproductive System Diagnoses with CC/MCC, relative weight 1.0544) and DRG 730 (Other Male Reproductive System Diagnoses without CC/MCC, relative weight 0.6597), in MDC 12 (Diseases and Disorders of the Male Reproductive System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

The Medicare Code Editor expects this diagnosis only for patients age 15 through 124.

It is on the CMS list of diagnoses consistent only with male patients (the sex-conflict edit itself was retired in FY2025).

It was added in FY2017, effective October 1, 2016.

Before ICD-10, this condition was coded in ICD-9-CM as 607.84 (Impotence of organic origin).