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ICD-10-CM 2027 diagnosis code

N80.522Deep endometriosis of the sigmoid colon

✓ Billable / specificFemale only

N80.522 is a valid, billable ICD-10-CM code for deep endometriosis of the sigmoid colon. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code last changed in FY2023 (effective October 1, 2022). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About N80.522

N80.522 is the ICD-10-CM diagnosis code for deep endometriosis of the sigmoid colon. It belongs to category N80 (endometriosis), block N80-N98 (noninflammatory disorders of female genital tract) and chapter 14 (diseases of the genitourinary system). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within N80.52 (endometriosis of the sigmoid colon), N80.522 is specifically for deep endometriosis of the sigmoid colon. Related codes cover superficial endometriosis of the sigmoid colon (N80.521) and unspecified depth (N80.529).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 391 (Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders with MCC, relative weight 1.2392) and DRG 392 (Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders without MCC, relative weight 0.7645), in MDC 06 (Diseases and Disorders of the Digestive System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It is on the CMS list of diagnoses consistent only with female patients (the sex-conflict edit itself was retired in FY2025).

It was added in FY2023, effective October 1, 2022.

Notes that apply from higher levels

Instructions written at a parent level also apply to N80.522.

Broader instructions also apply from Chapter 14: Diseases of the genitourinary system.

Alphabetic index entries

1 entries

Terms in the official ICD-10-CM index that lead to N80.522.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2023 (effective 10/1/2022): Added
  • No changes since FY2023.

Common questions about N80.522

Is N80.522 billable?

Yes. N80.522 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can N80.522 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict N80.522 as a principal diagnosis.

Is N80.522 a CC or MCC?

No. N80.522 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does N80.522 group to?

N80.522 is used in the MS-DRG v44.0 logic for MS-DRG 391 (Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders with MCC) and MS-DRG 392 (Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.