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ICD-10-CM 2027 diagnosis code

Q97.3Female with 46, XY karyotype

✓ Billable / specificPOA exemptFemale only

Q97.3 is a valid, billable ICD-10-CM code for female with 46, xy karyotype. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About Q97.3

Q97.3 is the ICD-10-CM diagnosis code for female with 46, XY karyotype. It belongs to category Q97 (other sex chromosome abnormalities, female phenotype, not elsewhere classified), block Q90-Q99 (chromosomal abnormalities, not elsewhere classified) and chapter 17 (congenital malformations, deformations, chromosomal abnormalities, and genetic disorders). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within Q97 (other sex chromosome abnormalities, female phenotype, not elsewhere classified), Q97.3 is specifically for female with 46, XY karyotype. Related codes cover karyotype 47, XXX (Q97.0), female with more than three X chromosomes (Q97.1), mosaicism, lines with various numbers of X chromosomes (Q97.2), other specified sex chromosome abnormalities, female phenotype (Q97.8) and sex chromosome abnormality, female phenotype, unspecified (Q97.9).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 742 (Uterine and Adnexa Procedures for Non-Malignancy with CC/MCC, relative weight 1.8456), DRG 743 (Uterine and Adnexa Procedures for Non-Malignancy without CC/MCC, relative weight 1.2974), DRG 760 (Menstrual and Other Female Reproductive System Disorders with CC/MCC, relative weight 1.0129) and DRG 761 (Menstrual and Other Female Reproductive System Disorders without CC/MCC, relative weight 0.7041), in MDC 13 (Diseases and Disorders of the Female Reproductive System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It is on the CMS list of diagnoses consistent only with female patients (the sex-conflict edit itself was retired in FY2025).

It is exempt from present-on-admission (POA) reporting, so no POA indicator is required.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 758.81 (other conditions due to sex chromosome anomalies).

Notes that apply from higher levels

Instructions written at a parent level also apply to Q97.3.

› From Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified
Excludes1
  • Turner's syndrome (Q96.-)

Broader instructions also apply from Q90-Q99 Chromosomal abnormalities, not elsewhere classified and Chapter 17: Congenital malformations, deformations, chromosomal abnormalities, and genetic disorders.

Alphabetic index entries

1 entries

Terms in the official ICD-10-CM index that lead to Q97.3.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 758.81Other conditions due to sex chromosome anomaliesapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about Q97.3

Is Q97.3 billable?

Yes. Q97.3 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can Q97.3 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict Q97.3 as a principal diagnosis.

Is Q97.3 a CC or MCC?

No. Q97.3 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does Q97.3 group to?

Q97.3 is used in the MS-DRG v44.0 logic for MS-DRG 742 (Uterine and Adnexa Procedures for Non-Malignancy with CC/MCC), MS-DRG 743 (Uterine and Adnexa Procedures for Non-Malignancy without CC/MCC), MS-DRG 760 (Menstrual and Other Female Reproductive System Disorders with CC/MCC) and MS-DRG 761 (Menstrual and Other Female Reproductive System Disorders without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for Q97.3?

The CMS General Equivalence Mappings map Q97.3 to ICD-9-CM 758.81.