ICD-10-CM 2027 diagnosis code
R50.2Drug induced fever
R50.2 is a valid, billable ICD-10-CM code for drug induced fever. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About R50.2
R50.2 is the ICD-10-CM diagnosis code for drug induced fever. It belongs to category R50 (fever of other and unknown origin), block R50-R69 (general symptoms and signs) and chapter 18 (symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
Within R50 (fever of other and unknown origin), R50.2 is specifically for drug induced fever. Related codes cover other specified fever (R50.8) and fever, unspecified (R50.9).
Don't report R50.2 together with the conditions in its Excludes1 note: postvaccination (postimmunization) fever (R50.83).
Use an additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 864 (Fever and Inflammatory Conditions, relative weight 0.8551), in MDC 18 (Infectious and Parasitic Diseases, Systemic or Unspecified Sites), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Before ICD-10, this condition was coded in ICD-9-CM as 780.60 (fever, unspecified) and E947.9 (unspecified drug or medicinal substance causing adverse effects in therapeutic use).
Coding notes
Notes that apply from higher levels
Instructions written at a parent level also apply to R50.2.
Broader instructions also apply from Chapter 18: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified.
Alphabetic index entries
5 entriesTerms in the official ICD-10-CM index that lead to R50.2.
- Drug › induced fever
- Fever (inanition) (of unknown origin) (persistent) (with chills) (with rigor) › drug induced
- Fever (inanition) (of unknown origin) (persistent) (with chills) (with rigor) › iodide
- Fever (inanition) (of unknown origin) (persistent) (with chills) (with rigor) › steroid
- Steroid › effects (adverse) (adrenocortical) (iatrogenic) › fever
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC 18 · Infectious and Parasitic Diseases, Systemic or Unspecified Sites
ICD-9-CM equivalent
Converter →- 780.60Fever, unspecifiedapproximate, combination
- E947.9Unspecified drug or medicinal substance causing adverse effects in therapeutic useapproximate, combination
From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about R50.2
Is R50.2 billable?
- Yes. R50.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can R50.2 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict R50.2 as a principal diagnosis.
Is R50.2 a CC or MCC?
- No. R50.2 is neither a CC nor an MCC under MS-DRG v44.0.
What DRG does R50.2 group to?
- R50.2 is used in the MS-DRG v44.0 logic for MS-DRG 864 (Fever and Inflammatory Conditions). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.
What is the ICD-9 code for R50.2?
- The CMS General Equivalence Mappings map R50.2 to ICD-9-CM 780.60 and E947.9.