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ICD-10-CM 2027 diagnosis code

R85.3Abnormal level of substances chiefly nonmedicinal as to source in specimens from digestive organs and abdominal cavity

✓ Billable / specific

R85.3 is a valid, billable ICD-10-CM code for abnormal level of substances chiefly nonmedicinal as to source in specimens from digestive organs and abdominal cavity. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.Short description: Abn lev substnc nonmed source in specmn fr dgstv org/abd cav

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About R85.3

R85.3 is the ICD-10-CM diagnosis code for abnormal level of substances chiefly nonmedicinal as to source in specimens from digestive organs and abdominal cavity. It belongs to category R85 (abnormal findings in specimens from digestive organs and abdominal cavity), block R83-R89 (abnormal findings on examination of other body fluids, substances and tissues, without diagnosis) and chapter 18 (symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within R85 (abnormal findings in specimens from digestive organs and abdominal cavity), R85.3 is specifically for abnormal level of substances chiefly nonmedicinal as to source in specimens from digestive organs and abdominal cavity. Related codes cover abnormal level of enzymes in specimens from digestive organs and abdominal cavity (R85.0), abnormal level of hormones in specimens from digestive organs and abdominal cavity (R85.1), abnormal level of other drugs, medicaments and biological substances in specimens from digestive organs and abdominal cavity (R85.2), abnormal immunological findings in specimens from digestive organs and abdominal cavity (R85.4), abnormal microbiological findings in specimens from digestive organs and abdominal cavity (R85.5), abnormal cytological findings in specimens from digestive organs and abdominal cavity (R85.6), abnormal histological findings in specimens from digestive organs and abdominal cavity (R85.7), other abnormal findings in specimens from digestive organs and abdominal cavity (R85.8) and 1 more.

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 947 (Signs and Symptoms with MCC, relative weight 1.261) and DRG 948 (Signs and Symptoms without MCC, relative weight 0.7835), in MDC 23 (Factors Influencing Health Status and Other Contacts with Health Services), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 792.4 (nonspecific abnormal findings in saliva) and 792.9 (other nonspecific abnormal findings in body substances).

Notes that apply from higher levels

Instructions written at a parent level also apply to R85.3.

› From R85 Abnormal findings in specimens from digestive organs and abdominal cavity
Includes
  • abnormal findings in peritoneal fluid
  • abnormal findings in saliva
Excludes1
  • cloudy peritoneal dialysis effluent (R88.0)
  • fecal abnormalities (R19.5)

Broader instructions also apply from R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis and Chapter 18: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified.

Alphabetic index entries

1 entries

Terms in the official ICD-10-CM index that lead to R85.3.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

MDC 23 · Factors Influencing Health Status and Other Contacts with Health Services

ICD-9-CM equivalent

Converter →
  • 792.4Nonspecific abnormal findings in salivaapproximate
  • 792.9Other nonspecific abnormal findings in body substancesapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about R85.3

Is R85.3 billable?

Yes. R85.3 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can R85.3 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict R85.3 as a principal diagnosis.

Is R85.3 a CC or MCC?

No. R85.3 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does R85.3 group to?

R85.3 is used in the MS-DRG v44.0 logic for MS-DRG 947 (Signs and Symptoms with MCC) and MS-DRG 948 (Signs and Symptoms without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for R85.3?

The CMS General Equivalence Mappings map R85.3 to ICD-9-CM 792.4 and 792.9.