S25.321AMajor laceration of right innominate or subclavian vein, initial encounter

S25.321A is the ICD-10-CM diagnosis code for major laceration of right innominate or subclavian vein, initial encounter. It belongs to category S25 (injury of blood vessels of thorax), block S20-S29 (injuries to the thorax) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

The 7th character "A" means initial encounter: use it while the patient is receiving active treatment for the condition.

As a secondary diagnosis it is an MCC (major complication or comorbidity), which can move an inpatient stay into the highest-paying "with MCC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 791 (Prematurity with Major Problems, relative weight 4.1075), DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195), DRG 913 (Traumatic Injury with MCC, relative weight 1.5455), DRG 914 (Traumatic Injury without MCC, relative weight 0.9285), DRG 963 (Other Multiple Significant Trauma with MCC, relative weight 2.6363), DRG 964 (Other Multiple Significant Trauma with CC, relative weight 1.4972) and 1 more, in MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), MDC 21 (Injuries, Poisonings and Toxic Effects of Drugs) and MDC 24 (Multiple Significant Trauma), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 901.3 (injury to innominate and subclavian veins).