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ICD-10-CM 2027 diagnosis code

T38.895Adverse effect of other hormones and synthetic substitutes

Not billable — use a more specific codeRequires 7th character

T38.895 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it and add the required 7th character.

Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS, effective October 1, 2026. Updated September 29, 2026. About our data

About T38.895

T38.895 is the ICD-10-CM diagnosis code for adverse effect of other hormones and synthetic substitutes. It belongs to category T38 (poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.

Within T38.89, choose T38.895 (Adverse effect of other hormones and synthetic substitutes) only when documentation doesn't support a more specific option: poisoning by other hormones and synthetic substitutes, accidental (unintentional) (T38.891), poisoning by other hormones and synthetic substitutes, intentional self-harm (T38.892), poisoning by other hormones and synthetic substitutes, assault (T38.893), poisoning by other hormones and synthetic substitutes, undetermined (T38.894) and underdosing of other hormones and synthetic substitutes (T38.896).

Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

7th character

The appropriate 7th character is to be added to each code from category T38

Notes that apply from higher levels

Instructions written at a parent level also apply to T38.895.

Table of Drugs & Neoplasms entries

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about T38.895

Is T38.895 billable?

No. T38.895 is a header code. Report one of its more specific subcodes instead.