ICD-10-CM 2027 diagnosis code
T40.49Poisoning by, adverse effect of and underdosing of other synthetic narcotics
T40.49 is a header code, so it can't be reported by itself. Choose one of the 6 more specific codes beneath it and add the required 7th character.Short description: Other synthetic narcotics
Code last changed in FY2021 (effective October 1, 2020). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About T40.49
T40.49 is the ICD-10-CM diagnosis code for poisoning by, adverse effect of and underdosing of other synthetic narcotics. It belongs to category T40 (poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens]), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 6 subcodes must be used instead.
Within T40.4, choose T40.49 (other synthetic narcotics) only when documentation doesn't support a more specific option: fentanyl or fentanyl analogs (T40.41) and tramadol (T40.42).
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
It was added in FY2021, effective October 1, 2020.
7th character
The appropriate 7th character is to be added to each code from category T40
- T40.491Poisoning by other synthetic narcotics, accidental (unintentional)
- T40.492Poisoning by other synthetic narcotics, intentional self-harm
- T40.493Poisoning by other synthetic narcotics, assault
- T40.494Poisoning by other synthetic narcotics, undetermined
- T40.495Adverse effect of other synthetic narcotics
- T40.496Underdosing of other synthetic narcotics
- Ainitial encounter
- Dsubsequent encounter
- Ssequela
Notes that apply from higher levels
Instructions written at a parent level also apply to T40.49.
Broader instructions also apply from T36-T50 Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances and Chapter 19: Injury, poisoning and certain other consequences of external causes.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2021 (effective 10/1/2020): Added
- No changes since FY2021.
Common questions about T40.49
Is T40.49 billable?
- No. T40.49 is a header code. Report one of its more specific subcodes instead.