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ICD-10-CM 2027 diagnosis code

T40.49Poisoning by, adverse effect of and underdosing of other synthetic narcotics

Not billable — use a more specific codeRequires 7th character

T40.49 is a header code, so it can't be reported by itself. Choose one of the 6 more specific codes beneath it and add the required 7th character.Short description: Other synthetic narcotics

Code last changed in FY2021 (effective October 1, 2020). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About T40.49

T40.49 is the ICD-10-CM diagnosis code for poisoning by, adverse effect of and underdosing of other synthetic narcotics. It belongs to category T40 (poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens]), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 6 subcodes must be used instead.

Within T40.4, choose T40.49 (other synthetic narcotics) only when documentation doesn't support a more specific option: fentanyl or fentanyl analogs (T40.41) and tramadol (T40.42).

Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.

It was added in FY2021, effective October 1, 2020.

7th character

The appropriate 7th character is to be added to each code from category T40

  • Ainitial encounter
  • Dsubsequent encounter
  • Ssequela

Notes that apply from higher levels

Instructions written at a parent level also apply to T40.49.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2021 (effective 10/1/2020): Added
  • No changes since FY2021.

Common questions about T40.49

Is T40.49 billable?

No. T40.49 is a header code. Report one of its more specific subcodes instead.