ICD-10-CM 2027 diagnosis code
T42.8X5Adverse effect of antiparkinsonism drugs and other central muscle-tone depressants
T42.8X5 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it and add the required 7th character.Short description: Adverse effect of antiparkns drug/centr muscle-tone depr
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About T42.8X5
T42.8X5 is the ICD-10-CM diagnosis code for adverse effect of antiparkinsonism drugs and other central muscle-tone depressants. It belongs to category T42 (poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.
Within T42.8X, choose T42.8X5 (Adverse effect of antiparkinsonism drugs and other central muscle-tone depressants) only when documentation doesn't support a more specific option: poisoning by antiparkinsonism drugs and other central muscle-tone depressants, accidental (unintentional) (T42.8X1), poisoning by antiparkinsonism drugs and other central muscle-tone depressants, intentional self-harm (T42.8X2), poisoning by antiparkinsonism drugs and other central muscle-tone depressants, assault (T42.8X3), poisoning by antiparkinsonism drugs and other central muscle-tone depressants, undetermined (T42.8X4) and underdosing of antiparkinsonism drugs and other central muscle-tone depressants (T42.8X6).
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
7th character
The appropriate 7th character is to be added to each code from category T42
Notes that apply from higher levels
Instructions written at a parent level also apply to T42.8X5.
Broader instructions also apply from T36-T50 Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances and Chapter 19: Injury, poisoning and certain other consequences of external causes.
Table of Drugs & Neoplasms entries
- Afloqualone — Adverse effect
- Amantadine — Adverse effect
- Antiparkinsonism drug NEC — Adverse effect
- Antirigidity drug NEC — Adverse effect
- Baclofen — Adverse effect
- Benserazide — Adverse effect
- Benzatropine — Adverse effect
- Benztropine › antiparkinson — Adverse effect
- Bromocriptine — Adverse effect
- Cabergoline — Adverse effect
- Carbidopa (with levodopa) — Adverse effect
- Carisoprodol — Adverse effect
- Central nervous system › depressants › muscle relaxants — Adverse effect
- Central nervous system › muscle-tone depressants — Adverse effect
- Chlorphenesin — Adverse effect
- Chlorzoxazone — Adverse effect
- Dantrolene — Adverse effect
- Deprenalin — Adverse effect
- Deprenyl — Adverse effect
- Depressant › central nervous system (anesthetic) › muscle tone — Adverse effect
- Depressant › muscle tone, central — Adverse effect
- Diethazine — Adverse effect
- Difluoromethyldopa — Adverse effect
- Disipal — Adverse effect
- Dopa — Adverse effect
- Idrocilamide — Adverse effect
- L-dopa — Adverse effect
- Levodopa — Adverse effect
- Levodopa › with carbidopa — Adverse effect
- Lisuride — Adverse effect
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about T42.8X5
Is T42.8X5 billable?
- No. T42.8X5 is a header code. Report one of its more specific subcodes instead.