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ICD-10-CM 2027 diagnosis code

T44.905SAdverse effect of unspecified drugs primarily affecting the autonomic nervous system, sequela

✓ Billable / specificPOA exemptRequires 7th characterNot a principal dx

T44.905S is a valid, billable ICD-10-CM code for adverse effect of unspecified drugs primarily affecting the autonomic nervous system, sequela. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.Short description: Advrs effect of unsp drugs aff the autonm nrv sys, sequela

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About T44.905S

T44.905S is the ICD-10-CM diagnosis code for adverse effect of unspecified drugs primarily affecting the autonomic nervous system, sequela. It belongs to category T44 (poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

The 7th character "S" means sequela: use it for complications or conditions that arise as a direct result of the original condition.

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 922 (Other Injury, Poisoning and Toxic Effect Diagnoses with MCC, relative weight 1.6238) and DRG 923 (Other Injury, Poisoning and Toxic Effect Diagnoses without MCC, relative weight 0.9973), in MDC 21 (Injuries, Poisonings and Toxic Effects of Drugs), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.

It is exempt from present-on-admission (POA) reporting, so no POA indicator is required.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 909.5 (late effect of adverse effect of drug, medicinal or biological substance) and E941.9 (unspecified drug primarily affecting the autonomic nervous system causing adverse effects in therapeutic use).

7th character

Ssequela

Other encounter types for T44.905:

Notes that apply from higher levels

Instructions written at a parent level also apply to T44.905S.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 909.5Late effect of adverse effect of drug, medicinal or biological substanceapproximate, combination
  • E941.9Unspecified drug primarily affecting the autonomic nervous system causing adverse effects in therapeutic useapproximate, combination

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about T44.905S

Is T44.905S billable?

Yes. T44.905S is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

What does the "S" at the end of T44.905S mean?

It is the 7th character for sequela. Per the official guidelines, use it for complications or conditions that arise as a direct result of the original condition.

Can T44.905S be used as a principal diagnosis?

No. It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.

Is T44.905S a CC or MCC?

No. T44.905S is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does T44.905S group to?

T44.905S is used in the MS-DRG v44.0 logic for MS-DRG 922 (Other Injury, Poisoning and Toxic Effect Diagnoses with MCC) and MS-DRG 923 (Other Injury, Poisoning and Toxic Effect Diagnoses without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for T44.905S?

The CMS General Equivalence Mappings map T44.905S to ICD-9-CM 909.5 and E941.9.