ICD-10-CM 2027 diagnosis code
T45.615Adverse effect of thrombolytic drugs
T45.615 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it and add the required 7th character.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About T45.615
T45.615 is the ICD-10-CM diagnosis code for adverse effect of thrombolytic drugs. It belongs to category T45 (poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.
Within T45.61 (poisoning by, adverse effect of and underdosing of thrombolytic drugs), T45.615 is specifically for adverse effect of thrombolytic drugs. Related codes cover poisoning by thrombolytic drug, accidental (unintentional) (T45.611), poisoning by thrombolytic drug, intentional self-harm (T45.612), poisoning by thrombolytic drug, assault (T45.613), poisoning by thrombolytic drug, undetermined (T45.614) and underdosing of thrombolytic drugs (T45.616).
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
7th character
The appropriate 7th character is to be added to each code from category T45
Notes that apply from higher levels
Instructions written at a parent level also apply to T45.615.
Table of Drugs & Neoplasms entries
- Alteplase — Adverse effect
- Anistreplase — Adverse effect
- Fibrinolytic drug — Adverse effect
- Plasminogen (tissue) activator — Adverse effect
- Rt-PA — Adverse effect
- Streptokinase — Adverse effect
- Thrombolysin — Adverse effect
- Urokinase — Adverse effect
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about T45.615
Is T45.615 billable?
- No. T45.615 is a header code. Report one of its more specific subcodes instead.