ICD-10-CM 2027 diagnosis code
T45.91Poisoning by unspecified primarily systemic and hematological agent, accidental (unintentional)
T45.91 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it and add the required 7th character.Short description: Poisn by unsp primarily systemic and hematolog agent, acc
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About T45.91
T45.91 is the ICD-10-CM diagnosis code for poisoning by unspecified primarily systemic and hematological agent, accidental (unintentional). It belongs to category T45 (poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.
Within T45.9, choose T45.91 (Poisoning by unspecified primarily systemic and hematological agent, accidental (unintentional)) only when documentation doesn't support a more specific option: poisoning by unspecified primarily systemic and hematological agent, intentional self-harm (T45.92), poisoning by unspecified primarily systemic and hematological agent, assault (T45.93), poisoning by unspecified primarily systemic and hematological agent, undetermined (T45.94), adverse effect of unspecified primarily systemic and hematological agent (T45.95) and underdosing of unspecified primarily systemic and hematological agent (T45.96).
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
7th character
The appropriate 7th character is to be added to each code from category T45
Coding notes
- Poisoning by primarily systemic and hematological agent NOS
Notes that apply from higher levels
Instructions written at a parent level also apply to T45.91.
Table of Drugs & Neoplasms entries
- Blood (derivatives) (natural) (plasma) (whole) › drug affecting NEC — Poisoning Accidental (unintentional)
- Hematological agent — Poisoning Accidental (unintentional)
- Systemic drug — Poisoning Accidental (unintentional)
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about T45.91
Is T45.91 billable?
- No. T45.91 is a header code. Report one of its more specific subcodes instead.