ICD-10-CM 2027 diagnosis code
T48.205Adverse effect of unspecified drugs acting on muscles
T48.205 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it and add the required 7th character.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About T48.205
T48.205 is the ICD-10-CM diagnosis code for adverse effect of unspecified drugs acting on muscles. It belongs to category T48 (poisoning by, adverse effect of and underdosing of agents primarily acting on smooth and skeletal muscles and the respiratory system), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.
Within T48.20, choose T48.205 (Adverse effect of unspecified drugs acting on muscles) only when documentation doesn't support a more specific option: poisoning by unspecified drugs acting on muscles, accidental (unintentional) (T48.201), poisoning by unspecified drugs acting on muscles, intentional self-harm (T48.202), poisoning by unspecified drugs acting on muscles, assault (T48.203), poisoning by unspecified drugs acting on muscles, undetermined (T48.204) and underdosing of unspecified drugs acting on muscles (T48.206).
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
7th character
The appropriate 7th character is to be added to each code from category T48
Notes that apply from higher levels
Instructions written at a parent level also apply to T48.205.
Table of Drugs & Neoplasms entries
- Muscle-action drug NEC — Adverse effect
- Muscle affecting agents NEC — Adverse effect
- Muscle affecting agents NEC › relaxants — Adverse effect
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about T48.205
Is T48.205 billable?
- No. T48.205 is a header code. Report one of its more specific subcodes instead.