ICD-10-CM 2027 diagnosis code
T48.4X5Adverse effect of expectorants
T48.4X5 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it and add the required 7th character.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About T48.4X5
T48.4X5 is the ICD-10-CM diagnosis code for adverse effect of expectorants. It belongs to category T48 (poisoning by, adverse effect of and underdosing of agents primarily acting on smooth and skeletal muscles and the respiratory system), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.
Within T48.4X (poisoning by, adverse effect of and underdosing of expectorants), T48.4X5 is specifically for adverse effect of expectorants. Related codes cover poisoning by expectorants, accidental (unintentional) (T48.4X1), poisoning by expectorants, intentional self-harm (T48.4X2), poisoning by expectorants, assault (T48.4X3), poisoning by expectorants, undetermined (T48.4X4) and underdosing of expectorants (T48.4X6).
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
7th character
The appropriate 7th character is to be added to each code from category T48
Notes that apply from higher levels
Instructions written at a parent level also apply to T48.4X5.
Table of Drugs & Neoplasms entries
- Acetylcysteine — Adverse effect
- Ambroxol — Adverse effect
- Ammonium › chloride › expectorant — Adverse effect
- Bromhexine — Adverse effect
- Calcium › iodide — Adverse effect
- Carbocisteine — Adverse effect
- S-Carboxymethyl-cysteine — Adverse effect
- Cough mixture (syrup) — Adverse effect
- Cough mixture (syrup) › expectorants — Adverse effect
- Creosote (coal tar) (beechwood) › medicinal (expectorant) — Adverse effect
- Creosote (coal tar) (beechwood) › syrup — Adverse effect
- Deglycyrrhizinized extract of licorice — Adverse effect
- Domiodol — Adverse effect
- Dornase — Adverse effect
- Eprazinone — Adverse effect
- Expectorant NEC — Adverse effect
- Glycerol › iodinated — Adverse effect
- Glyceryl › gualacolate — Adverse effect
- Glycyrrhiza extract — Adverse effect
- Glycyrrhizic acid — Adverse effect
- Glycyrrhizinate potassium — Adverse effect
- Guaiacol derivatives — Adverse effect
- Guaifenesin — Adverse effect
- Guaimesal — Adverse effect
- Guaiphenesin — Adverse effect
- Hydriodic acid — Adverse effect
- Iodide NEC › potassium (expectorant) NEC — Adverse effect
- Iodinated › glycerol — Adverse effect
- Ipecacuanha — Adverse effect
- Letosteine — Adverse effect
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about T48.4X5
Is T48.4X5 billable?
- No. T48.4X5 is a header code. Report one of its more specific subcodes instead.