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ICD-10-CM 2027 diagnosis code

T49.95Adverse effect of unspecified topical agent

Not billable — use a more specific codeRequires 7th character

T49.95 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it and add the required 7th character.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About T49.95

T49.95 is the ICD-10-CM diagnosis code for adverse effect of unspecified topical agent. It belongs to category T49 (poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.

Within T49.9, choose T49.95 (Adverse effect of unspecified topical agent) only when documentation doesn't support a more specific option: poisoning by unspecified topical agent, accidental (unintentional) (T49.91), poisoning by unspecified topical agent, intentional self-harm (T49.92), poisoning by unspecified topical agent, assault (T49.93), poisoning by unspecified topical agent, undetermined (T49.94) and underdosing of unspecified topical agent (T49.96).

Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

7th character

The appropriate 7th character is to be added to each code from category T49

Notes that apply from higher levels

Instructions written at a parent level also apply to T49.95.

Table of Drugs & Neoplasms entries

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about T49.95

Is T49.95 billable?

No. T49.95 is a header code. Report one of its more specific subcodes instead.