ICD-10-CM 2027 diagnosis code
T50.905Adverse effect of unspecified drugs, medicaments and biological substances
T50.905 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it and add the required 7th character.Short description: Adverse effect of unsp drug/meds/biol subst
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About T50.905
T50.905 is the ICD-10-CM diagnosis code for adverse effect of unspecified drugs, medicaments and biological substances. It belongs to category T50 (poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.
Within T50.90, choose T50.905 (Adverse effect of unspecified drugs, medicaments and biological substances) only when documentation doesn't support a more specific option: poisoning by unspecified drugs, medicaments and biological substances, accidental (unintentional) (T50.901), poisoning by unspecified drugs, medicaments and biological substances, intentional self-harm (T50.902), poisoning by unspecified drugs, medicaments and biological substances, assault (T50.903), poisoning by unspecified drugs, medicaments and biological substances, undetermined (T50.904) and underdosing of unspecified drugs, medicaments and biological substances (T50.906).
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
7th character
The appropriate 7th character is to be added to each code from category T50
Notes that apply from higher levels
Instructions written at a parent level also apply to T50.905.
Table of Drugs & Neoplasms entries
- Acidifying agent NEC — Adverse effect
- Adjunct, pharmaceutical — Adverse effect
- Alkalinizing agents (medicinal) — Adverse effect
- Alkalizing agent NEC — Adverse effect
- Biological substance NEC — Adverse effect
- Dietetic drug NEC — Adverse effect
- Drug NEC — Adverse effect
- Dye NEC › pharmaceutical NEC — Adverse effect
- Elemental diet — Adverse effect
- Excipients, pharmaceutical — Adverse effect
- Headache cures, drugs, powders NEC — Adverse effect
- Lactose (as excipient) — Adverse effect
- Lipotropic drug NEC — Adverse effect
- Medicament NEC — Adverse effect
- Nutritional supplement — Adverse effect
- Pharmaceutical › adjunct NEC — Adverse effect
- Pharmaceutical › excipient NEC — Adverse effect
- Pharmaceutical › sweetener — Adverse effect
- Pharmaceutical › viscous agent — Adverse effect
- Preservative (nonmedicinal) › medicinal — Adverse effect
- Saccharin — Adverse effect
- Salt substitute — Adverse effect
- Salt-replacing drug — Adverse effect
- Sodium-free salt — Adverse effect
- Soothing syrup — Adverse effect
- Spray (aerosol) › medicinal NEC — Adverse effect
- Starch — Adverse effect
- Stone-dissolving drug — Adverse effect
- Sweetener — Adverse effect
- Tablets — Adverse effect
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about T50.905
Is T50.905 billable?
- No. T50.905 is a header code. Report one of its more specific subcodes instead.