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ICD-10-CM 2027 diagnosis code

T50.995Adverse effect of other drugs, medicaments and biological substances

Not billable — use a more specific codeRequires 7th character

T50.995 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it and add the required 7th character.Short description: Adverse effect of drug/meds/biol subst

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About T50.995

T50.995 is the ICD-10-CM diagnosis code for adverse effect of other drugs, medicaments and biological substances. It belongs to category T50 (poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.

Within T50.99, choose T50.995 (Adverse effect of other drugs, medicaments and biological substances) only when documentation doesn't support a more specific option: poisoning by other drugs, medicaments and biological substances, accidental (unintentional) (T50.991), poisoning by other drugs, medicaments and biological substances, intentional self-harm (T50.992), poisoning by other drugs, medicaments and biological substances, assault (T50.993), poisoning by other drugs, medicaments and biological substances, undetermined (T50.994) and underdosing of other drugs, medicaments and biological substances (T50.996).

Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

7th character

The appropriate 7th character is to be added to each code from category T50

Notes that apply from higher levels

Instructions written at a parent level also apply to T50.995.

Table of Drugs & Neoplasms entries

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about T50.995

Is T50.995 billable?

No. T50.995 is a header code. Report one of its more specific subcodes instead.