ICD-10-CM 2027 diagnosis code
T50.Z15Adverse effect of immunoglobulin
T50.Z15 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it and add the required 7th character.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About T50.Z15
T50.Z15 is the ICD-10-CM diagnosis code for adverse effect of immunoglobulin. It belongs to category T50 (poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances), block T36-T50 (poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.
Within T50.Z1 (poisoning by, adverse effect of and underdosing of immunoglobulin), T50.Z15 is specifically for adverse effect of immunoglobulin. Related codes cover poisoning by immunoglobulin, accidental (unintentional) (T50.Z11), poisoning by immunoglobulin, intentional self-harm (T50.Z12), poisoning by immunoglobulin, assault (T50.Z13), poisoning by immunoglobulin, undetermined (T50.Z14) and underdosing of immunoglobulin (T50.Z16).
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
7th character
The appropriate 7th character is to be added to each code from category T50
Notes that apply from higher levels
Instructions written at a parent level also apply to T50.Z15.
Table of Drugs & Neoplasms entries
- AHLG — Adverse effect
- Anti-D immunoglobulin (human) — Adverse effect
- Antidiphtheria serum — Adverse effect
- Anti-human lymphocytic globulin — Adverse effect
- Antirabies hyperimmune serum — Adverse effect
- Antiscorpion sera — Adverse effect
- Antitetanus immunoglobulin — Adverse effect
- Antitoxin — Adverse effect
- Antitoxin › diphtheria — Adverse effect
- Antitoxin › gas gangrene — Adverse effect
- Antitoxin › tetanus — Adverse effect
- Antivenin, antivenom (sera) — Adverse effect
- Antivenin, antivenom (sera) › crotaline — Adverse effect
- Antivenin, antivenom (sera) › spider bite — Adverse effect
- Black › widow spider (bite) › antivenin — Adverse effect
- Botulinus anti-toxin (type A, B) — Adverse effect
- Diphtheria › antitoxin — Adverse effect
- Gamimune — Adverse effect
- Gamma globulin — Adverse effect
- Gamulin — Adverse effect
- Globulin › antilymphocytic — Adverse effect
- Globulin › antirhesus — Adverse effect
- Globulin › antivenin — Adverse effect
- Globulin › antiviral — Adverse effect
- Hepatitis B › immune globulin — Adverse effect
- Homo-tet — Adverse effect
- Horse anti-human lymphocytic serum — Adverse effect
- Human › immune serum — Adverse effect
- Hypertussis — Adverse effect
- lmmu-G — Adverse effect
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about T50.Z15
Is T50.Z15 billable?
- No. T50.Z15 is a header code. Report one of its more specific subcodes instead.