T80.6Other serum reactions

T80.6 is the ICD-10-CM diagnosis code for other serum reactions. It belongs to category T80 (complications following infusion, transfusion and therapeutic injection), block T80-T88 (complications of surgical and medical care, not elsewhere classified) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.

Within T80, choose T80.6 (Other serum reactions) only when documentation doesn't support a more specific option: air embolism following infusion, transfusion and therapeutic injection (T80.0), vascular complications following infusion, transfusion and therapeutic injection (T80.1), infections following infusion, transfusion and therapeutic injection (T80.2), ABO incompatibility reaction due to transfusion of blood or blood products (T80.3), Rh incompatibility reaction due to transfusion of blood or blood products (T80.4), anaphylactic reaction due to serum (T80.5), other complications following infusion, transfusion and therapeutic injection (T80.8), unspecified complication following infusion, transfusion and therapeutic injection (T80.9) and 1 more.

Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.

The conditions in its Excludes2 note aren't part of T80.6, but may be coded alongside it if the patient has both: serum hepatitis (B16-B19).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.