ICD-10-CM 2027 diagnosis code
Z16.34Resistance to antimycobacterial drug(s)
Z16.34 is a header code, so it can't be reported by itself. Choose one of the 2 more specific codes beneath it.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About Z16.34
Z16.34 is the ICD-10-CM diagnosis code for resistance to antimycobacterial drug(s). It belongs to category Z16 (resistance to antimicrobial drugs), block Z16 (resistance to antimicrobial drugs) and chapter 21 (factors influencing health status and contact with health services). It is a header code, so it can't be reported by itself; one of its 2 subcodes must be used instead.
Within Z16.3 (resistance to other antimicrobial drugs), Z16.34 is specifically for resistance to antimycobacterial drug(s). Related codes cover unspecified antimicrobial drugs (Z16.30), antiparasitic drug(s) (Z16.31), antifungal drug(s) (Z16.32), antiviral drug(s) (Z16.33), multiple antimicrobial drugs (Z16.35) and other specified antimicrobial drug (Z16.39).
To report this condition, pick the subcode that matches the documentation: Z16.341 (drug) and Z16.342 (drugs).
Code first: the infection.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under Z16.34
Coding notes
- Resistance to tuberculostatics
Notes that apply from higher levels
Instructions written at a parent level also apply to Z16.34.
› From Z16 Resistance to antimicrobial drugs
- The codes in this category are provided for use as additional codes to identify the resistance and non-responsiveness of a condition to antimicrobial drugs.
- the infection
Broader instructions also apply from Chapter 21: Factors influencing health status and contact with health services.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about Z16.34
Is Z16.34 billable?
- No. Z16.34 is a header code. Report one of its more specific subcodes instead.