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ICD-10-CM 2027 diagnosis code

Z29.1Encounter for prophylactic immunotherapy

Not billable — use a more specific code

Z29.1 is a header code, so it can't be reported by itself. Choose one of the 4 more specific codes beneath it.

Code last changed in FY2017 (effective October 1, 2016). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About Z29.1

Z29.1 is the ICD-10-CM diagnosis code for encounter for prophylactic immunotherapy. It belongs to category Z29 (encounter for other prophylactic measures), block Z20-Z29 (persons with potential health hazards related to communicable diseases) and chapter 21 (factors influencing health status and contact with health services). It is a header code, so it can't be reported by itself; one of its 4 subcodes must be used instead.

Within Z29 (encounter for other prophylactic measures), Z29.1 is specifically for encounter for prophylactic immunotherapy. Related codes cover prophylactic fluoride administration (Z29.3), other specified prophylactic measures (Z29.8) and prophylactic measures, unspecified (Z29.9).

To report this condition, pick the subcode that matches the documentation: Z29.11 (for respiratory syncytial virus (RSV)), Z29.12 (antivenin), Z29.13 (globulin) and Z29.14 (globulin).

It was added in FY2017, effective October 1, 2016.

Specific codes under Z29.1

Coding notes

Applicable toConditions and synonyms classified to this code
  • Encounter for administration of immunoglobulin

Notes that apply from higher levels

Instructions written at a parent level also apply to Z29.1.

› From Z29 Encounter for other prophylactic measures
Excludes1
  • desensitization to allergens (Z51.6)
  • prophylactic surgery (Z40.-)

Broader instructions also apply from Chapter 21: Factors influencing health status and contact with health services.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2017 (effective 10/1/2016): Added
  • No changes since FY2017.

Common questions about Z29.1

Is Z29.1 billable?

No. Z29.1 is a header code. Report one of its more specific subcodes instead.