Z92.850Personal history of Chimeric Antigen Receptor T-cell therapy

Z92.850 is the ICD-10-CM diagnosis code for personal history of Chimeric Antigen Receptor T-cell therapy. It belongs to category Z92 (personal history of medical treatment), block Z77-Z99 (persons with potential health hazards related to family and personal history and certain conditions influencing health status) and chapter 21 (factors influencing health status and contact with health services). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within Z92.85 (personal history of cellular therapy), Z92.850 is specifically for personal history of Chimeric Antigen Receptor T-cell therapy. Related codes cover other cellular therapy (Z92.858) and unspecified (Z92.859).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 951 (Other Factors Influencing Health Status, relative weight 0.5577), in MDC 23 (Factors Influencing Health Status and Other Contacts with Health Services), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.

It is exempt from present-on-admission (POA) reporting, so no POA indicator is required.

It was added in FY2022, effective October 1, 2021.