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ICD-10-CM 2027

ICD-10 code for acute graft-versus-host disease

D89.810

Acute graft-versus-host disease

From the official ICD-10-CM alphabetic index entry “Graft-versus-host disease › acute”. Page updated September 29, 2026.

About coding acute graft-versus-host disease

The ICD-10-CM code for acute graft-versus-host disease is D89.810 (Acute graft-versus-host disease).

Within D89.81 (graft-versus-host disease), D89.810 is specifically for acute graft-versus-host disease. Related codes cover chronic graft-versus-host disease (D89.811), acute on chronic graft-versus-host disease (D89.812) and unspecified (D89.813).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 808 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with MCC, relative weight 2.1705), DRG 809 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with CC, relative weight 1.2262) and DRG 810 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders without CC/MCC, relative weight 1.075), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

Common questions about acute graft-versus-host disease ICD-10 codes

What is the ICD-10 code for acute graft-versus-host disease?

D89.810 — Acute graft-versus-host disease.

Is D89.810 billable?

Yes. D89.810 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can D89.810 be used as a principal diagnosis?

No. It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.

Is D89.810 a CC or MCC?

D89.810 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.