ICD-10-CM 2027
ICD-10 code for Adenopathy
From the official ICD-10-CM alphabetic index entry “Adenopathy (lymph gland)”. Page updated September 29, 2026.
About coding Adenopathy
The ICD-10-CM code for Adenopathy is R59.9 (Enlarged lymph nodes, unspecified). The official index lists 11 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on R59.9.
Within R59, choose R59.9 (unspecified) only when documentation doesn't support a more specific option: localized enlarged lymph nodes (R59.0) and generalized enlarged lymph nodes (R59.1).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 814 (Reticuloendothelial and Immunity Disorders with MCC, relative weight 2.0729), DRG 815 (Reticuloendothelial and Immunity Disorders with CC, relative weight 1.0444) and DRG 816 (Reticuloendothelial and Immunity Disorders without CC/MCC, relative weight 0.7381), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific Adenopathy codes (official index)
- generalized R59.1 — Generalized enlarged lymph nodes
- inguinal R59.0 — Localized enlarged lymph nodes
- localized R59.0 — Localized enlarged lymph nodes
- mediastinal R59.0 — Localized enlarged lymph nodes
- mesentery R59.0 — Localized enlarged lymph nodes
- syphilitic (secondary) A51.49 — Other secondary syphilitic conditions
- tracheobronchial R59.0 — Localized enlarged lymph nodes
- tuberculous A15.4 — Tuberculosis of intrathoracic lymph nodes
- primary (progressive) A15.7 — Primary respiratory tuberculosis
- tuberculous
- tracheobronchial A15.4 — Tuberculosis of intrathoracic lymph nodes
- primary (progressive) A15.7 — Primary respiratory tuberculosis
Common questions about Adenopathy ICD-10 codes
What is the ICD-10 code for Adenopathy?
- R59.9 — Enlarged lymph nodes, unspecified. More specific codes apply when the documentation supports them: R59.1, R59.0, R59.0, R59.0 and others below.
What is the ICD-10 code for generalized adenopathy?
- R59.1 — Generalized enlarged lymph nodes.
What is the ICD-10 code for inguinal adenopathy?
- R59.0 — Localized enlarged lymph nodes.
What is the ICD-10 code for localized adenopathy?
- R59.0 — Localized enlarged lymph nodes.
What is the ICD-10 code for mediastinal adenopathy?
- R59.0 — Localized enlarged lymph nodes.
What is the ICD-10 code for mesentery adenopathy?
- R59.0 — Localized enlarged lymph nodes.
What is the ICD-10 code for syphilitic adenopathy?
- A51.49 — Other secondary syphilitic conditions.
Is R59.9 billable?
- Yes. R59.9 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can R59.9 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict R59.9 as a principal diagnosis.
Is R59.9 a CC or MCC?
- No. R59.9 is neither a CC nor an MCC under MS-DRG v44.0.