ICD-10-CM 2027 diagnosis code
R59Enlarged lymph nodes
R59 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About R59
R59 is the ICD-10-CM diagnosis code for enlarged lymph nodes. It belongs to block R50-R69 (general symptoms and signs) and chapter 18 (symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.
To report this condition, pick the subcode that matches the documentation: R59.0 (nodes), R59.1 (nodes) and R59.9 (unspecified).
Don't report R59 together with the conditions in its Excludes1 note: lymphadenitis NOS (I88.9), acute lymphadenitis (L04.-), chronic lymphadenitis (I88.1) and mesenteric (acute) (chronic) lymphadenitis (I88.0).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under R59
Coding notes
Notes that apply from higher levels
Instructions written at a parent level also apply to R59.
Broader instructions also apply from Chapter 18: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified.
Codes whose notes reference R59
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about R59
Is R59 billable?
- No. R59 is a header code. Report one of its more specific subcodes instead.