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ICD-10-CM 2027

ICD-10 code for Agitated depression

F32.2

Major depressive disorder, single episode, severe without psychotic features

✓ Billable / specificCC — complication/comorbidity

From the official ICD-10-CM alphabetic index entry “Depression (acute) (mental) › agitated (single episode)”. Page updated September 29, 2026.

About coding Agitated depression

The ICD-10-CM code for Agitated depression is F32.2 (Major depressive disorder, single episode, severe without psychotic features).

Within F32, choose F32.2 (Major depressive disorder, single episode, severe without psychotic features) only when documentation doesn't support a more specific option: major depressive disorder, single episode, mild (F32.0), major depressive disorder, single episode, moderate (F32.1), major depressive disorder, single episode, severe with psychotic features (F32.3), major depressive disorder, single episode, in partial remission (F32.4), major depressive disorder, single episode, in full remission (F32.5), other depressive episodes (F32.8), major depressive disorder, single episode, unspecified (F32.9) and depression, unspecified (F32.A).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 885 (Psychoses, relative weight 1.3901), in MDC 19 (Mental Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

Common questions about Agitated depression ICD-10 codes

What is the ICD-10 code for Agitated depression?

F32.2 — Major depressive disorder, single episode, severe without psychotic features.

Is F32.2 billable?

Yes. F32.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can F32.2 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict F32.2 as a principal diagnosis.

Is F32.2 a CC or MCC?

F32.2 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.