F32.3Major depressive disorder, single episode, severe with psychotic features

F32.3 is the ICD-10-CM diagnosis code for major depressive disorder, single episode, severe with psychotic features. It belongs to category F32 (depressive episode), block F30-F39 (mood [affective] disorders) and chapter 5 (mental, Behavioral and Neurodevelopmental disorders). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within F32 (depressive episode), F32.3 is specifically for major depressive disorder, single episode, severe with psychotic features. Related codes cover major depressive disorder, single episode, mild (F32.0), major depressive disorder, single episode, moderate (F32.1), major depressive disorder, single episode, severe without psychotic features (F32.2), major depressive disorder, single episode, in partial remission (F32.4), major depressive disorder, single episode, in full remission (F32.5), other depressive episodes (F32.8), major depressive disorder, single episode, unspecified (F32.9) and depression, unspecified (F32.A).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 885 (Psychoses, relative weight 1.3901), in MDC 19 (Mental Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 296.24 (major depressive affective disorder, single episode, severe, specified as with psychotic behavior) and 298.0 (depressive type psychosis).