ICD-10-CM 2027
ICD-10 code for Agitated state
From the official ICD-10-CM alphabetic index entry “State (of) › agitated”. Page updated September 29, 2026.
About coding Agitated state
The ICD-10-CM code for Agitated state is R45.1 (Restlessness and agitation). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on R45.1.
Within R45 (symptoms and signs involving emotional state), R45.1 is specifically for Restlessness and agitation. Related codes cover Nervousness (R45.0), unhappiness (R45.2), Demoralization and apathy (R45.3), irritability and anger (R45.4), Hostility (R45.5), Violent behavior (R45.6), state of emotional shock and stress, unspecified (R45.7) and other symptoms and signs involving emotional state (R45.8).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 884 (Organic Disturbances and Intellectual Disability, relative weight 1.6001), in MDC 19 (Mental Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific Agitated state codes (official index)
- acute reaction to stress F43.0 — Acute stress reaction
Common questions about Agitated state ICD-10 codes
What is the ICD-10 code for Agitated state?
- R45.1 — Restlessness and agitation. More specific codes apply when the documentation supports them: F43.0.
What is the ICD-10 code for acute reaction to stress agitated state?
- F43.0 — Acute stress reaction.
Is R45.1 billable?
- Yes. R45.1 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can R45.1 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict R45.1 as a principal diagnosis.
Is R45.1 a CC or MCC?
- No. R45.1 is neither a CC nor an MCC under MS-DRG v44.0.