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ICD-10-CM 2027 diagnosis code

R45Symptoms and signs involving emotional state

Not billable — use a more specific code

R45 is a header code, so it can't be reported by itself. Choose one of the 9 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About R45

R45 is the ICD-10-CM diagnosis code for symptoms and signs involving emotional state. It belongs to block R40-R46 (symptoms and signs involving cognition, perception, emotional state and behavior) and chapter 18 (symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified). It is a header code, so it can't be reported by itself; one of its 9 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: R45.0 (Nervousness), R45.1 (agitation), R45.2 (unhappiness), R45.3 (apathy), R45.4 (anger), R45.5 (Hostility), R45.6 (behavior), R45.7 (unspecified) and 1 more.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under R45

Notes that apply from higher levels

Instructions written at a parent level also apply to R45.

Broader instructions also apply from R40-R46 Symptoms and signs involving cognition, perception, emotional state and behavior and Chapter 18: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified.

Codes whose notes reference R45

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about R45

Is R45 billable?

No. R45 is a header code. Report one of its more specific subcodes instead.