ICD-10-CM 2027
ICD-10 code for Anaerobic sepsis
From the official ICD-10-CM alphabetic index entry “Sepsis (generalized) (unspecified organism) › anaerobic”. Page updated September 29, 2026.
About coding Anaerobic sepsis
The ICD-10-CM code for Anaerobic sepsis is A41.4 (Sepsis due to anaerobes).
Within A41 (other sepsis), A41.4 is specifically for sepsis due to anaerobes. Related codes cover sepsis due to Staphylococcus aureus (A41.0), sepsis due to other specified staphylococcus (A41.1), sepsis due to unspecified staphylococcus (A41.2), sepsis due to Hemophilus influenzae (A41.3), sepsis due to other Gram-negative organisms (A41.5), other specified sepsis (A41.8) and sepsis, unspecified organism (A41.9).
Don't report A41.4 together with the conditions in its Excludes1 note: gas gangrene (A48.0).
Code first: , if applicable, postprocedural sepsis (T81.44-), sepsis due to central venous catheter (T80.211-), sepsis during labor (O75.3), sepsis following abortion, ectopic or molar pregnancy (O03.37, O03.87, O04.87, O07.37, O08.82) and 2 more.
Don't confuse with (Excludes1 for A41.4)
- gas gangrene (A48.0)
Common questions about Anaerobic sepsis ICD-10 codes
What is the ICD-10 code for Anaerobic sepsis?
- A41.4 — Sepsis due to anaerobes.
Is A41.4 billable?
- Yes. A41.4 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can A41.4 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict A41.4 as a principal diagnosis.
Is A41.4 a CC or MCC?
- A41.4 is an MCC (major complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.