ICD-10-CM 2027
ICD-10 code for antibiotics long-term drug therapy
From the official ICD-10-CM alphabetic index entry “Long-term (current) (prophylactic) drug therapy (use of) › antibiotics”. Page updated September 29, 2026.
About coding antibiotics long-term drug therapy
The ICD-10-CM code for antibiotics long-term drug therapy is Z79.2 (Long term (current) use of antibiotics).
Within Z79 (long term (current) drug therapy), Z79.2 is specifically for long term (current) use of antibiotics. Related codes cover long term (current) use of anticoagulants and antithrombotics/antiplatelets (Z79.0), long term (current) use of non-steroidal anti-inflammatories (NSAID) (Z79.1), long term (current) use of hormonal contraceptives (Z79.3), long term (current) use of insulin (Z79.4), long term (current) use of steroids (Z79.5), long term (current) use of immunomodulators and immunosuppressants (Z79.6) and other long term (current) drug therapy (Z79.8).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 949 (Aftercare with CC/MCC, relative weight 1.123) and DRG 950 (Aftercare without CC/MCC, relative weight 0.7664), in MDC 23 (Factors Influencing Health Status and Other Contacts with Health Services), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific antibiotics long-term drug therapy codes (official index)
- short-term use - omit code
Common questions about antibiotics long-term drug therapy ICD-10 codes
What is the ICD-10 code for antibiotics long-term drug therapy?
- Z79.2 — Long term (current) use of antibiotics.
Is Z79.2 billable?
- Yes. Z79.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can Z79.2 be used as a principal diagnosis?
- No. It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.
Is Z79.2 a CC or MCC?
- No. Z79.2 is neither a CC nor an MCC under MS-DRG v44.0.