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ICD-10-CM 2027 diagnosis code

Z79.6Long term (current) use of immunomodulators and immunosuppressants

Not billable — use a more specific code

Z79.6 is a header code, so it can't be reported by itself. Choose one of the 6 more specific codes beneath it.Short description: Long term (crnt) use of immunomodulator & immunosuppressant

Code last changed in FY2023 (effective October 1, 2022). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About Z79.6

Z79.6 is the ICD-10-CM diagnosis code for long term (current) use of immunomodulators and immunosuppressants. It belongs to category Z79 (long term (current) drug therapy), block Z77-Z99 (persons with potential health hazards related to family and personal history and certain conditions influencing health status) and chapter 21 (factors influencing health status and contact with health services). It is a header code, so it can't be reported by itself; one of its 6 subcodes must be used instead.

Within Z79 (long term (current) drug therapy), Z79.6 is specifically for long term (current) use of immunomodulators and immunosuppressants. Related codes cover long term (current) use of anticoagulants and antithrombotics/antiplatelets (Z79.0), long term (current) use of non-steroidal anti-inflammatories (NSAID) (Z79.1), long term (current) use of antibiotics (Z79.2), long term (current) use of hormonal contraceptives (Z79.3), long term (current) use of insulin (Z79.4), long term (current) use of steroids (Z79.5) and other long term (current) drug therapy (Z79.8).

To report this condition, pick the subcode that matches the documentation: Z79.60 (immunosuppressants), Z79.61 (immunomodulator), Z79.62 (immunosuppressant), Z79.63 (agent), Z79.64 (agent) and Z79.69 (immunosuppressants).

The conditions in its Excludes2 note aren't part of Z79.6, but may be coded alongside it if the patient has both: long term (current) use of steroids (Z79.5-) and long term (current) use of agents affecting estrogen receptors and estrogen levels (Z79.81-).

It was added in FY2023, effective October 1, 2022.

Specific codes under Z79.6

Coding notes

Excludes2Not included here — may be reported together if both conditions exist
  • long term (current) use of steroids (Z79.5-)
  • long term (current) use of agents affecting estrogen receptors and estrogen levels (Z79.81-)

Notes that apply from higher levels

Instructions written at a parent level also apply to Z79.6.

› From Z79 Long term (current) drug therapy
Includes
  • long term (current) drug use for prophylactic purposes
Excludes2
  • drug abuse and dependence (F11-F19)
  • drug use complicating pregnancy, childbirth, and the puerperium (O99.32-)
Code also
  • any therapeutic drug level monitoring (Z51.81)

Broader instructions also apply from Z77-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status and Chapter 21: Factors influencing health status and contact with health services.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2023 (effective 10/1/2022): Added
  • No changes since FY2023.

Common questions about Z79.6

Is Z79.6 billable?

No. Z79.6 is a header code. Report one of its more specific subcodes instead.