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ICD-10-CM 2027

ICD-10 code for Anticardiolipin syndrome

D68.61

Antiphospholipid syndrome

✓ Billable / specificCC — complication/comorbidity

From the official ICD-10-CM alphabetic index entry “Anticardiolipin syndrome”. Page updated September 29, 2026.

About coding Anticardiolipin syndrome

The ICD-10-CM code for Anticardiolipin syndrome is D68.61 (Antiphospholipid syndrome).

Within D68.6 (other thrombophilia), D68.61 is specifically for Antiphospholipid syndrome. Related codes cover lupus anticoagulant syndrome (D68.62) and other thrombophilia (D68.69).

Don't report D68.61 together with the conditions in its Excludes1 note: anti-phospholipid antibody, finding without diagnosis (R76.0).

The conditions in its Excludes2 note aren't part of D68.61, but may be coded alongside it if the patient has both: anti-phospholipid antibody with hemorrhagic disorder (D68.312) and lupus anticoagulant syndrome (D68.62).

Don't confuse with (Excludes1 for D68.61)

  • anti-phospholipid antibody, finding without diagnosis (R76.0)

Common questions about Anticardiolipin syndrome ICD-10 codes

What is the ICD-10 code for Anticardiolipin syndrome?

D68.61 — Antiphospholipid syndrome.

Is D68.61 billable?

Yes. D68.61 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can D68.61 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict D68.61 as a principal diagnosis.

Is D68.61 a CC or MCC?

D68.61 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.