D68.312Antiphospholipid antibody with hemorrhagic disorder

D68.312 is the ICD-10-CM diagnosis code for Antiphospholipid antibody with hemorrhagic disorder. It belongs to category D68 (other coagulation defects), block D65-D69 (coagulation defects, purpura and other hemorrhagic conditions) and chapter 3 (diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within D68.31 (hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors), D68.312 is specifically for Antiphospholipid antibody with hemorrhagic disorder. Related codes cover acquired hemophilia (D68.311) and other hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors (D68.318).

Don't report D68.312 together with the conditions in its Excludes1 note: antiphospholipid antibody, finding without diagnosis (R76.0), lupus anticoagulant (LAC) finding without diagnosis (R76.0) and systemic lupus erythematosus [SLE] inhibitor finding without diagnosis (R76.0).

The conditions in its Excludes2 note aren't part of D68.312, but may be coded alongside it if the patient has both: antiphospholipid antibody syndrome (D68.61), antiphospholipid antibody with hypercoagulable state (D68.61), lupus anticoagulant (LAC) with hypercoagulable state (D68.62) and systemic lupus erythematosus [SLE] inhibitor with hypercoagulable state (D68.62).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 814 (Reticuloendothelial and Immunity Disorders with MCC, relative weight 2.0729), DRG 815 (Reticuloendothelial and Immunity Disorders with CC, relative weight 1.0444) and DRG 816 (Reticuloendothelial and Immunity Disorders without CC/MCC, relative weight 0.7381), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 286.53 (Antiphospholipid antibody with hemorrhagic disorder).