ICD-10-CM 2027
ICD-10 code for Antithrombin deficiency hypercoagulable
From the official ICD-10-CM alphabetic index entry “Hypercoagulable (state) › antithrombin (III) deficiency”. Page updated September 29, 2026.
About coding Antithrombin deficiency hypercoagulable
The ICD-10-CM code for Antithrombin deficiency hypercoagulable is D68.59 (Other primary thrombophilia).
Within D68.5, choose D68.59 (Other primary thrombophilia) only when documentation doesn't support a more specific option: activated protein C resistance (D68.51) and Prothrombin gene mutation (D68.52).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 814 (Reticuloendothelial and Immunity Disorders with MCC, relative weight 2.0729), DRG 815 (Reticuloendothelial and Immunity Disorders with CC, relative weight 1.0444) and DRG 816 (Reticuloendothelial and Immunity Disorders without CC/MCC, relative weight 0.7381), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about Antithrombin deficiency hypercoagulable ICD-10 codes
What is the ICD-10 code for Antithrombin deficiency hypercoagulable?
- D68.59 — Other primary thrombophilia.
Is D68.59 billable?
- Yes. D68.59 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D68.59 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D68.59 as a principal diagnosis.
Is D68.59 a CC or MCC?
- D68.59 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.