ICD-10-CM 2027
ICD-10 code for anus asc-us
Atypical squamous cells of undetermined significance on cytologic smear of anus (ASC-US)
From the official ICD-10-CM alphabetic index entry “ASC-US (atypical squamous cells of undetermined significance on cytologic smear) › anus”. Page updated September 29, 2026.
About coding anus asc-us
The ICD-10-CM code for anus asc-us is R85.610 (Atypical squamous cells of undetermined significance on cytologic smear of anus (ASC-US)).
Within R85.61 (abnormal cytologic smear of anus), R85.610 is specifically for atypical squamous cells of undetermined significance on cytologic smear of anus (ASC-US). Related codes cover atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of anus (ASC-H) (R85.611), low grade squamous intraepithelial lesion on cytologic smear of anus (LGSIL) (R85.612), high grade squamous intraepithelial lesion on cytologic smear of anus (HGSIL) (R85.613), cytologic evidence of malignancy on smear of anus (R85.614), unsatisfactory cytologic smear of anus (R85.615), Satisfactory anal smear but lacking transformation zone (R85.616), other abnormal cytological findings on specimens from anus (R85.618) and unspecified abnormal cytological findings in specimens from anus (R85.619).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 393 (Other Digestive System Diagnoses with MCC, relative weight 1.5881), DRG 394 (Other Digestive System Diagnoses with CC, relative weight 0.9228) and DRG 395 (Other Digestive System Diagnoses without CC/MCC, relative weight 0.6382), in MDC 06 (Diseases and Disorders of the Digestive System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about anus asc-us ICD-10 codes
What is the ICD-10 code for anus asc-us?
- R85.610 — Atypical squamous cells of undetermined significance on cytologic smear of anus (ASC-US).
Is R85.610 billable?
- Yes. R85.610 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can R85.610 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict R85.610 as a principal diagnosis.
Is R85.610 a CC or MCC?
- No. R85.610 is neither a CC nor an MCC under MS-DRG v44.0.