ICD-10-CM 2027 diagnosis code
R85.61Abnormal cytologic smear of anus
R85.61 is a header code, so it can't be reported by itself. Choose one of the 9 more specific codes beneath it.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About R85.61
R85.61 is the ICD-10-CM diagnosis code for abnormal cytologic smear of anus. It belongs to category R85 (abnormal findings in specimens from digestive organs and abdominal cavity), block R83-R89 (abnormal findings on examination of other body fluids, substances and tissues, without diagnosis) and chapter 18 (symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified). It is a header code, so it can't be reported by itself; one of its 9 subcodes must be used instead.
Within R85.6 (abnormal cytological findings in specimens from digestive organs and abdominal cavity), R85.61 is specifically for abnormal cytologic smear of anus. Related codes cover cytological findings in specimens from other digestive organs and abdominal cavity (R85.69).
To report this condition, pick the subcode that matches the documentation: R85.610 ((ASC-US)), R85.611 ((ASC-H)), R85.612 ((LGSIL)), R85.613 ((HGSIL)), R85.614 (anus), R85.615 (anus), R85.616 (zone), R85.618 (anus) and 1 more.
Don't report R85.61 together with the conditions in its Excludes1 note: abnormal cytological findings in specimens from other digestive organs and abdominal cavity (R85.69), carcinoma in situ of anus (histologically confirmed) (D01.3), anal intraepithelial neoplasia I [AIN I] (K62.82), anal intraepithelial neoplasia II [AIN II] (K62.82) and 3 more.
The conditions in its Excludes2 note aren't part of R85.61, but may be coded alongside it if the patient has both: anal high risk human papillomavirus (HPV) DNA test positive (R85.81) and anal low risk human papillomavirus (HPV) DNA test positive (R85.82).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under R85.61
- R85.610Atypical squamous cells of undetermined significance on cytologic smear of anus (ASC-US)Billable
- R85.611Atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of anus (ASC-H)Billable
- R85.612Low grade squamous intraepithelial lesion on cytologic smear of anus (LGSIL)Billable
- R85.613High grade squamous intraepithelial lesion on cytologic smear of anus (HGSIL)Billable
- R85.614Cytologic evidence of malignancy on smear of anusBillable
- R85.615Unsatisfactory cytologic smear of anusBillable
- R85.616Satisfactory anal smear but lacking transformation zoneBillable
- R85.618Other abnormal cytological findings on specimens from anusBillable
- R85.619Unspecified abnormal cytological findings in specimens from anusBillable
Coding notes
- abnormal cytological findings in specimens from other digestive organs and abdominal cavity (R85.69)
- carcinoma in situ of anus (histologically confirmed) (D01.3)
- anal intraepithelial neoplasia I [AIN I] (K62.82)
- anal intraepithelial neoplasia II [AIN II] (K62.82)
- anal intraepithelial neoplasia III [AIN III] (D01.3)
- dysplasia (mild) (moderate) of anus (histologically confirmed) (K62.82)
- severe dysplasia of anus (histologically confirmed) (D01.3)
Notes that apply from higher levels
Instructions written at a parent level also apply to R85.61.
Broader instructions also apply from R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis and Chapter 18: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified.
Codes whose notes reference R85.61
- K62.82Excludes1
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about R85.61
Is R85.61 billable?
- No. R85.61 is a header code. Report one of its more specific subcodes instead.