ICD-10-CM 2027
ICD-10 code for B-cell lymphoma
Unspecified B-cell lymphoma, unspecified site
Confirmed by the official ICD-10-CM index entry “lymphoma (of) (malignant) › b-cell”. Page updated September 29, 2026.
About coding B-cell lymphoma
The ICD-10-CM code for B-cell lymphoma is C85.10 (Unspecified B-cell lymphoma, unspecified site). The official index lists 22 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on C85.10.
Within C85.1, choose C85.10 (unspecified site) only when documentation doesn't support a more specific option: lymph nodes of head, face, and neck (C85.11), intrathoracic lymph nodes (C85.12), intra-abdominal lymph nodes (C85.13), lymph nodes of axilla and upper limb (C85.14), lymph nodes of inguinal region and lower limb (C85.15), intrapelvic lymph nodes (C85.16), spleen (C85.17), lymph nodes of multiple sites (C85.18) and 2 more.
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 820 (Lymphoma and Leukemia with Major O.R. Procedures with MCC, relative weight 6.2481), DRG 821 (Lymphoma and Leukemia with Major O.R. Procedures with CC, relative weight 2.2023), DRG 822 (Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC, relative weight 1.1272), DRG 823 (Lymphoma and Non-Acute Leukemia with Other Procedures with MCC, relative weight 4.6059), DRG 824 (Lymphoma and Non-Acute Leukemia with Other Procedures with CC, relative weight 2.2515), DRG 825 (Lymphoma and Non-Acute Leukemia with Other Procedures without CC/MCC, relative weight 1.2995) and 6 more, in MDC 17 (Myeloproliferative Diseases and Disorders, Poorly Differentiated Neoplasms) and MDC 25 (Human Immunodeficiency Virus Infections), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Related B-cell lymphoma codes
- C83.30 Diffuse large B-cell lymphoma, unspecified site
- C83.31 Diffuse large B-cell lymphoma, lymph nodes of head, face, and neck
- C83.32 Diffuse large B-cell lymphoma, intrathoracic lymph nodes
- C83.33 Diffuse large B-cell lymphoma, intra-abdominal lymph nodes
- C83.34 Diffuse large B-cell lymphoma, lymph nodes of axilla and upper limb
- C83.35 Diffuse large B-cell lymphoma, lymph nodes of inguinal region and lower limb
- C83.36 Diffuse large B-cell lymphoma, intrapelvic lymph nodes
- C83.37 Diffuse large B-cell lymphoma, spleen
- C83.38 Diffuse large B-cell lymphoma, lymph nodes of multiple sites
- C83.390 Primary central nervous system lymphoma
- C83.398 Diffuse large B-cell lymphoma of other extranodal and solid organ sites
- C83.3A Diffuse large B-cell lymphoma, in remission
- C85.11 Unspecified B-cell lymphoma, lymph nodes of head, face, and neck
- C85.12 Unspecified B-cell lymphoma, intrathoracic lymph nodes
- C85.13 Unspecified B-cell lymphoma, intra-abdominal lymph nodes
- C85.14 Unspecified B-cell lymphoma, lymph nodes of axilla and upper limb
- C85.15 Unspecified B-cell lymphoma, lymph nodes of inguinal region and lower limb
- C85.16 Unspecified B-cell lymphoma, intrapelvic lymph nodes
- C85.17 Unspecified B-cell lymphoma, spleen
- C85.18 Unspecified B-cell lymphoma, lymph nodes of multiple sites
- C85.19 Unspecified B-cell lymphoma, extranodal and solid organ sites
- C85.1A Unspecified B-cell lymphoma, in remission
Common questions about B-cell lymphoma ICD-10 codes
What is the ICD-10 code for B-cell lymphoma?
- C85.10 — Unspecified B-cell lymphoma, unspecified site. More specific codes apply when the documentation supports them: C83.30, C83.31, C83.32, C83.33 and others below.
What is the ICD-10 code for diffuse large b-cell lymphoma, unspecified site?
- C83.30 — Diffuse large B-cell lymphoma, unspecified site.
What is the ICD-10 code for diffuse large b-cell lymphoma, lymph nodes of head, face, and neck?
- C83.31 — Diffuse large B-cell lymphoma, lymph nodes of head, face, and neck.
What is the ICD-10 code for diffuse large b-cell lymphoma, intrathoracic lymph nodes?
- C83.32 — Diffuse large B-cell lymphoma, intrathoracic lymph nodes.
What is the ICD-10 code for diffuse large b-cell lymphoma, intra-abdominal lymph nodes?
- C83.33 — Diffuse large B-cell lymphoma, intra-abdominal lymph nodes.
What is the ICD-10 code for diffuse large b-cell lymphoma, lymph nodes of axilla and upper limb?
- C83.34 — Diffuse large B-cell lymphoma, lymph nodes of axilla and upper limb.
What is the ICD-10 code for diffuse large b-cell lymphoma, lymph nodes of inguinal region and lower limb?
- C83.35 — Diffuse large B-cell lymphoma, lymph nodes of inguinal region and lower limb.
Is C85.10 billable?
- Yes. C85.10 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can C85.10 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict C85.10 as a principal diagnosis.
Is C85.10 a CC or MCC?
- C85.10 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.