ICD-10-CM 2027
ICD-10 code for Big spleen syndrome
From the official ICD-10-CM alphabetic index entry “Big spleen syndrome”. Page updated September 29, 2026.
About coding Big spleen syndrome
The ICD-10-CM code for Big spleen syndrome is D73.1 (Hypersplenism).
Within D73 (diseases of spleen), D73.1 is specifically for Hypersplenism. Related codes cover Hyposplenism (D73.0), chronic congestive splenomegaly (D73.2), abscess of spleen (D73.3), cyst of spleen (D73.4), infarction of spleen (D73.5), other diseases of spleen (D73.8) and disease of spleen, unspecified (D73.9).
Don't report D73.1 together with the conditions in its Excludes1 note: neutropenic splenomegaly (D73.81), primary splenic neutropenia (D73.81), splenitis, splenomegaly in late syphilis (A52.79), splenitis, splenomegaly in tuberculosis (A18.85) and 2 more.
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
Don't confuse with (Excludes1 for D73.1)
Common questions about Big spleen syndrome ICD-10 codes
What is the ICD-10 code for Big spleen syndrome?
- D73.1 — Hypersplenism.
Is D73.1 billable?
- Yes. D73.1 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D73.1 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D73.1 as a principal diagnosis.
Is D73.1 a CC or MCC?
- No. D73.1 is neither a CC nor an MCC under MS-DRG v44.0.