ICD-10-CM 2027
ICD-10 code for biochemical pregnancy
Inappropriate change in quantitative human chorionic gonadotropin (hCG) in early pregnancy
From the official ICD-10-CM alphabetic index entry “Pregnancy (single) (uterine) › biochemical”. Page updated September 29, 2026.
About coding biochemical pregnancy
The ICD-10-CM code for biochemical pregnancy is O02.81 (Inappropriate change in quantitative human chorionic gonadotropin (hCG) in early pregnancy).
Within O02.8 (other specified abnormal products of conception), O02.81 is specifically for inappropriate change in quantitative human chorionic gonadotropin (hCG) in early pregnancy. Related codes cover other abnormal products of conception (O02.89).
Use an additional code from category O08 to identify any associated complication.
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
Common questions about biochemical pregnancy ICD-10 codes
What is the ICD-10 code for biochemical pregnancy?
- O02.81 — Inappropriate change in quantitative human chorionic gonadotropin (hCG) in early pregnancy.
Is O02.81 billable?
- Yes. O02.81 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can O02.81 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict O02.81 as a principal diagnosis.
Is O02.81 a CC or MCC?
- No. O02.81 is neither a CC nor an MCC under MS-DRG v44.0.