ICD-10-CM 2027
ICD-10 code for bone cryptococcosis
From the official ICD-10-CM alphabetic index entry “Cryptococcosis, cryptococcus (infection) (neoformans) › bone”. Page updated September 29, 2026.
About coding bone cryptococcosis
The ICD-10-CM code for bone cryptococcosis is B45.3 (Osseous cryptococcosis).
Within B45 (cryptococcosis), B45.3 is specifically for osseous cryptococcosis. Related codes cover pulmonary cryptococcosis (B45.0), cerebral cryptococcosis (B45.1), cutaneous cryptococcosis (B45.2), disseminated cryptococcosis (B45.7), other forms of cryptococcosis (B45.8) and unspecified (B45.9).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 791 (Prematurity with Major Problems, relative weight 4.1075), DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195), DRG 867 (Other Infectious and Parasitic Diseases Diagnoses with MCC, relative weight 2.1859), DRG 868 (Other Infectious and Parasitic Diseases Diagnoses with CC, relative weight 1.0235), DRG 869 (Other Infectious and Parasitic Diseases Diagnoses without CC/MCC, relative weight 0.6787), DRG 974 (HIV with Major Related Condition with MCC, relative weight 3.0506) and 2 more, in MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), MDC 18 (Infectious and Parasitic Diseases, Systemic or Unspecified Sites) and MDC 25 (Human Immunodeficiency Virus Infections), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about bone cryptococcosis ICD-10 codes
What is the ICD-10 code for bone cryptococcosis?
- B45.3 — Osseous cryptococcosis.
Is B45.3 billable?
- Yes. B45.3 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can B45.3 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict B45.3 as a principal diagnosis.
Is B45.3 a CC or MCC?
- B45.3 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.