B45.9Cryptococcosis, unspecified

B45.9 is the ICD-10-CM diagnosis code for cryptococcosis, unspecified. It belongs to category B45 (cryptococcosis), block B35-B49 (mycoses) and chapter 1 (certain infectious and parasitic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within B45, choose B45.9 (unspecified) only when documentation doesn't support a more specific option: pulmonary cryptococcosis (B45.0), cerebral cryptococcosis (B45.1), cutaneous cryptococcosis (B45.2), osseous cryptococcosis (B45.3), disseminated cryptococcosis (B45.7) and other forms of cryptococcosis (B45.8).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 791 (Prematurity with Major Problems, relative weight 4.1075), DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195), DRG 867 (Other Infectious and Parasitic Diseases Diagnoses with MCC, relative weight 2.1859), DRG 868 (Other Infectious and Parasitic Diseases Diagnoses with CC, relative weight 1.0235), DRG 869 (Other Infectious and Parasitic Diseases Diagnoses without CC/MCC, relative weight 0.6787), DRG 974 (HIV with Major Related Condition with MCC, relative weight 3.0506) and 2 more, in MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), MDC 18 (Infectious and Parasitic Diseases, Systemic or Unspecified Sites) and MDC 25 (Human Immunodeficiency Virus Infections), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 117.5 (cryptococcosis).