ICD-10-CM 2027
ICD-10 code for bone generalisata xanthoma
Multifocal and unisystemic Langerhans-cell histiocytosis
From the official ICD-10-CM alphabetic index entry “Xanthoma (s), xanthomatosis (primary) (familial) (hereditary) › bone (generalisata)”. Page updated September 29, 2026.
About coding bone generalisata xanthoma
The ICD-10-CM code for bone generalisata xanthoma is C96.5 (Multifocal and unisystemic Langerhans-cell histiocytosis).
Within C96 (other and unspecified malignant neoplasms of lymphoid, hematopoietic and related tissue), C96.5 is specifically for multifocal and unisystemic Langerhans-cell histiocytosis. Related codes cover multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis (C96.0), malignant mast cell neoplasm (C96.2), sarcoma of dendritic cells (accessory cells) (C96.4), Unifocal Langerhans-cell histiocytosis (C96.6), malignant neoplasm of lymphoid, hematopoietic and related tissue, unspecified (C96.9), histiocytic sarcoma (C96.A) and other specified malignant neoplasms of lymphoid, hematopoietic and related tissue (C96.Z).
Don't report C96.5 together with the conditions in its Excludes1 note: multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis (C96.0) and unifocal Langerhans-cell histiocytosis (C96.6).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
Don't confuse with (Excludes1 for C96.5)
Common questions about bone generalisata xanthoma ICD-10 codes
What is the ICD-10 code for bone generalisata xanthoma?
- C96.5 — Multifocal and unisystemic Langerhans-cell histiocytosis.
Is C96.5 billable?
- Yes. C96.5 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can C96.5 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict C96.5 as a principal diagnosis.
Is C96.5 a CC or MCC?
- C96.5 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.