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ICD-10-CM 2027

ICD-10 code for Colloid nodule

E04.1

Nontoxic single thyroid nodule

✓ Billable / specific

From the official ICD-10-CM alphabetic index entry “Colloid nodule (of thyroid) (cystic)”. Page updated September 29, 2026.

About coding Colloid nodule

The ICD-10-CM code for Colloid nodule is E04.1 (Nontoxic single thyroid nodule).

Within E04 (other nontoxic goiter), E04.1 is specifically for nontoxic single thyroid nodule. Related codes cover nontoxic diffuse goiter (E04.0), nontoxic multinodular goiter (E04.2), other specified nontoxic goiter (E04.8) and nontoxic goiter, unspecified (E04.9).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 011 (Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy with MCC, relative weight 5.6154), DRG 012 (Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy with CC, relative weight 4.381), DRG 013 (Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy without CC/MCC, relative weight 2.7307), DRG 643 (Endocrine Disorders with MCC, relative weight 1.6139), DRG 644 (Endocrine Disorders with CC, relative weight 1.0044) and DRG 645 (Endocrine Disorders without CC/MCC, relative weight 0.7459), in Pre-MDC and MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

Common questions about Colloid nodule ICD-10 codes

What is the ICD-10 code for Colloid nodule?

E04.1 — Nontoxic single thyroid nodule.

Is E04.1 billable?

Yes. E04.1 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E04.1 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E04.1 as a principal diagnosis.

Is E04.1 a CC or MCC?

No. E04.1 is neither a CC nor an MCC under MS-DRG v44.0.