ICD-10-CM 2027
ICD-10 code for cytopenia
From the official ICD-10-CM alphabetic index entry “Cytopenia”. Page updated September 29, 2026.
About coding cytopenia
The ICD-10-CM code for cytopenia is D75.9 (Disease of blood and blood-forming organs, unspecified). The official index lists 2 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on D75.9.
Within D75, choose D75.9 (Disease of blood and blood-forming organs, unspecified) only when documentation doesn't support a more specific option: familial erythrocytosis (D75.0), secondary polycythemia (D75.1), other specified diseases of blood and blood-forming organs (D75.8) and glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia (D75.A).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 814 (Reticuloendothelial and Immunity Disorders with MCC, relative weight 2.0729), DRG 815 (Reticuloendothelial and Immunity Disorders with CC, relative weight 1.0444) and DRG 816 (Reticuloendothelial and Immunity Disorders without CC/MCC, relative weight 0.7381), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific cytopenia codes (official index)
Common questions about cytopenia ICD-10 codes
What is the ICD-10 code for cytopenia?
- D75.9 — Disease of blood and blood-forming organs, unspecified. More specific codes apply when the documentation supports them: D46.A, D46.B.
Is D75.9 billable?
- Yes. D75.9 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D75.9 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D75.9 as a principal diagnosis.
Is D75.9 a CC or MCC?
- No. D75.9 is neither a CC nor an MCC under MS-DRG v44.0.