ICD-10-CM 2027
ICD-10 code for Diphasic anemia
From the official ICD-10-CM alphabetic index entry “Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › diphasic”. Page updated September 29, 2026.
About coding Diphasic anemia
The ICD-10-CM code for Diphasic anemia is D53.1 (Other megaloblastic anemias, not elsewhere classified).
Within D53, choose D53.1 (Other megaloblastic anemias, not elsewhere classified) only when documentation doesn't support a more specific option: protein deficiency anemia (D53.0), Scorbutic anemia (D53.2), other specified nutritional anemias (D53.8) and nutritional anemia, unspecified (D53.9).
Don't report D53.1 together with the conditions in its Excludes1 note: Di Guglielmo's disease (C94.0).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
Don't confuse with (Excludes1 for D53.1)
- Di Guglielmo's disease (C94.0)
Common questions about Diphasic anemia ICD-10 codes
What is the ICD-10 code for Diphasic anemia?
- D53.1 — Other megaloblastic anemias, not elsewhere classified.
Is D53.1 billable?
- Yes. D53.1 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D53.1 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D53.1 as a principal diagnosis.
Is D53.1 a CC or MCC?
- No. D53.1 is neither a CC nor an MCC under MS-DRG v44.0.