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ICD-10-CM 2027

ICD-10 code for ectopic ACTH syndrome

E24.3

Ectopic ACTH syndrome

✓ Billable / specificCC — complication/comorbidity

From the official ICD-10-CM alphabetic index entry “Syndrome › ectopic ACTH”. Page updated September 29, 2026.

About coding ectopic ACTH syndrome

The ICD-10-CM code for ectopic ACTH syndrome is E24.3 (Ectopic ACTH syndrome).

Within E24 (Cushing's syndrome), E24.3 is specifically for ectopic ACTH syndrome. Related codes cover Pituitary-dependent Cushing's disease (E24.0), Nelson's syndrome (E24.1), drug-induced Cushing's syndrome (E24.2), alcohol-induced pseudo-Cushing's syndrome (E24.4), other Cushing's syndrome (E24.8) and unspecified (E24.9).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 643 (Endocrine Disorders with MCC, relative weight 1.6139), DRG 644 (Endocrine Disorders with CC, relative weight 1.0044) and DRG 645 (Endocrine Disorders without CC/MCC, relative weight 0.7459), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

Common questions about ectopic ACTH syndrome ICD-10 codes

What is the ICD-10 code for ectopic ACTH syndrome?

E24.3 — Ectopic ACTH syndrome.

Is E24.3 billable?

Yes. E24.3 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E24.3 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E24.3 as a principal diagnosis.

Is E24.3 a CC or MCC?

E24.3 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.